Epigenetic Advancements in Cancer
von Springer International Publishing
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Beschreibung
This volume explores the epigenetic alterations and their association with various human cancers. Considering one of human cancer as an example, individual chapters are focused on defining the role of epigenetic regulators and underlying mechanisms in cancer growth and progression. Epigenetic alteration including DNA methylation, histone modification, nucleosome positioning and non-coding RNAs expression are involved in a complex network of regulating expression of oncogenes and tumor suppressor genes and constitute an important event of the multistep process of carcinogenesis. Recent advances in the understanding of the epigenetic regulation and detailed information of these epigenetic changes in various cancers provide new avenues of advancements in diagnostics, prognostics, and therapies of this highly fatal disease.
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Anmerkung Illustrationen:
XI, 246 p. 12 illus., 11 illus. in color.
Inhaltsverzeichnis:
1. Role of DNA methylation in the progression and clearance of cancer.- 2. Epigenetical role for RNA in cancer progression.- 3. Epigenetics and its role in prostate cancer.- 4. Epigenetics and ovarian cancer.- 5. Epigenetics and breast cancer.- 6. Epigenetics and thyroid cancer.- 7. Epigenetics and intestinal cancer.- 8. Epigenetics and lung cancer.- 9. Epigenetics and renal cancer.- 10. Epigenetics and cervical cancer.- 11. Epigenetical markers in cancer.- 12. Epigenetical role in pancreatic cancer.
Herausgeber:
Mishra, Manoj K.;Mishra
Bishnupuri, Kumar S.;Bishnupuri
Bemerkungen:
Explores epigenetic landscape that occur in various cancer cells and the role of these changes in cancer initiation and progression
Discusses recent technological advancements that allow epigenetic alterations in cancer to be studied across the entire genome
Covers a spectrum of human cancers, including prostate, ovarian, breast, gastric, pancreatic, and more
Discusses recent technological advancements that allow epigenetic alterations in cancer to be studied across the entire genome
Covers a spectrum of human cancers, including prostate, ovarian, breast, gastric, pancreatic, and more
Medientyp:
Buch gebunden
Verlag:
Springer International Publishing
Biografie:
Manoj K. Mishra, Ph.D., is Associate Professor of Biology and founding Director of the cancer biology research and training program at Alabama State University. He has published over 25 articles, over 30 abstracts and poster exhibits, co-edited a book on Gene Regulation and Cancer, and has written over 5 book chapters. Dr. Mishra is on multiple ed boards, including the European Journal of Bioinformatics, Advances in Medical Informatics, and the International Journal of Experimental Medicine, to name a few.
Kumar S. Bishnupuri, Ph.D., is a Research Instructor in the Department of Medicine at Washington University School of Medicine. Dr. Bishnupuri has published over 16 articles, 4 book chapters, and 32 abstracts for conference symposia. He also serves as a scientific reviewer for several journals including Carcinogenesis, Frontiers in Bioscience, Cancer Biology and Therapy, Journal of Pathology, and more.
Kumar S. Bishnupuri, Ph.D., is a Research Instructor in the Department of Medicine at Washington University School of Medicine. Dr. Bishnupuri has published over 16 articles, 4 book chapters, and 32 abstracts for conference symposia. He also serves as a scientific reviewer for several journals including Carcinogenesis, Frontiers in Bioscience, Cancer Biology and Therapy, Journal of Pathology, and more.
Sprache:
Englisch
Auflage:
1st ed. 2016
Seitenanzahl:
246
Stammdaten
Produkttyp :
Buch Gebunden
Verpackungsabmessungen:
0.24 x 0.164 x 0.02 m; 0.536 kg
GTIN:
09783319249490
DUIN:
5E86VKH7HAJ
€ 139,40